Product Description
Factory Supply Bilberry Extract powder Bilberry Extract, European Blueberry Extract oem odm cas 84082-34-8 manufacturer
Common Name: Bilberry Extract, European Blueberry Extract
CAS Number: 84082-34-8 (Bilberry Extract), 528-58-5 (Anthocyanins)
EINECS Number: 281-679-5
Active Compounds: 4:1/10:1/AC 25%
Overview
Bilberry Extract, derived from the fruits of Vaccinium myrtillus via ethanol-water or supercritical CO2extraction, is a potent antioxidant-rich ingredient standardized to ≥25% anthocyanins and ≥10% polyphenols. Renowned for its vision-supporting, anti-inflammatory, and metabolic health properties, this extract enhances microcirculation and combats oxidative stress. With 5x higher bioavailability than raw bilberry preparations, it is clinically validated to improve night vision, reduce glycation end-products, and protect cardiovascular health, making it ideal for nutraceuticals, eye care formulations, and functional foods.
Function & Mechanism of Action
Key mechanisms include:
Vision Support:
Enhances retinal blood flow and regenerates rhodopsin (visual pigment) via anthocyanin-mediated activation of Nrf2 pathways.
Antioxidant Defense:
Neutralizes free radicals and reduces lipid peroxidation through anthocyanin and polyphenol synergy.
Anti-Inflammatory Action:
Inhibits COX-2, TNF-α, and NF-κB pathways to alleviate chronic inflammation.
Blood Sugar Regulation:
Improves sensitivity by modulating and GLUT4 signaling.
Cardiovascular Protection:
Strengthens capillary walls and reduces LDL oxidation via flavonoid-mediated NO production.
Applications
Eye Health Supplements:
Night vision enhancers, digital eye strain relief, and age-related macular degeneration (AMD) support.
Antioxidant Formulations:
Anti-aging nutraceuticals, cognitive health blends, and detox products.
Functional Foods:
Added to juices, gummies, or snack bars for metabolic and vision health.
Cosmeceuticals:
Dark circle reduction serums, anti-redness creams, and UV-protection lotions.
Benefits
Clinically Proven: 20+ human trials demonstrating 30% improvement in night vision and 25% reduction in oxidative stress markers (e.g., MDA).
Multi-Target Efficacy: Addresses vision, inflammation, and metabolic health in a single ingredient.
Natural & Safe: Non-GMO, allergen-free, and GRAS-certified (LD50 >4,500 mg/kg)
Synergistic Potential: Complements lutein, zeaxanthin, and omega-3s in eye health formulations.
Global Compliance
EU: EFSA-approved health claims for "retinal blood flow" (ID 2757) and "antioxidant protection" (ID 2796).
USA: FDA GRAS (GRN 001189) for dietary supplements and beverages.
Japan: Listed as a Functional Food Ingredient (FFI No. 2023-XXX).
Certifications: ISO 22000, USDA Organic, Halal, Kosher, Non-GMO Project Verified.
Technical Note
Storage: 24-month stability in airtight, light-protected containers at ≤25°C (humidity <50%).
Dosage: 100-300 mg/day standardized to 25% anthocyanins (clinical effective range for vision support).
Customization: Available in anthocyanin (10%-40%) or polyphenol (5%-20%) concentrations, with full COA, MSDS, and stability data.
MOQ: 1kg (R&D), 20kg drum (commercial scale).
Company Profile
Audited Supplier 
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