Product Description
Factory Supply Pomegranate Extract powder Pomegranate Fruit Extract, Punica granatum Extract oem odm cas 84961-57-9 manufacturer
Common Name: Pomegranate Fruit Extract, Punica granatum Extract
CAS Number: 84961-57-9 (Pomegranate Extract), 476-66-4 (Ellagic Acid)
EINECS Number: 284-511-6
Active Compounds: ≥40% Punicalagins, ≥10% Ellagic Acid (by HPLC
Overview
Pomegranate Extract, derived from the fruit and peel of Punica granatum via ethanol-water or supercritical CO extraction, is a potent antioxidant-rich ingredient standardized to ≥40% punicalagins and ≥10% ellagic acid. Renowned for its cardiovascular, anti-aging, and anti-inflammatory properties, this extract enhances nitric oxide synthesis and combats oxidative stress. With 4x higher bioavailability than raw pomegranate preparations, it is clinically validated to support heart health, skin vitality, and metabolic balance, making it a premier choice for nutraceuticals, cosmeceuticals, and functional foods.
Function & Mechanism of Action
Key mechanisms include:
Antioxidant Defense:
Neutralizes free radicals via punicalagin-mediated activation of Nrf2 pathways and regenerates glutathione (GSH).
Cardiovascular Protection:
Improves endothelial function by enhancing nitric oxide (NO) bioavailability and reducing LDL oxidation.
Anti-Inflammatory Action:
Inhibits NF-κB and COX-2 pathways, lowering pro-inflammatory cytokines (TNF-α, IL-6).
Anti-Aging & Skin Health:
Stimulates collagen synthesis and inhibits MMP-1 to reduce wrinkles and UV-induced damage.
Anticancer Potential:
Induces apoptosis in cancer cells via p53 activation and suppresses angiogenesis ( inhibition).
Applications
Cardiovascular Supplements:
Blood pressure management, cholesterol-lowering blends, and endothelial support formulas.
Anti-Aging Cosmeceuticals:
Collagen-boosting serums, UV-protection creams, and hyperpigmentation treatments.
Functional Foods:
Antioxidant juices, snack bars, and beverages for metabolic health.
Pharmaceuticals:
Adjuvant therapy for prostate health, diabetes, and cancer prevention.
Benefits
Clinically Proven: 30+ human trials demonstrating 20% reduction in systolic blood pressure and 35% improvement in skin elasticity.
Multi-Target Efficacy: Addresses oxidative stress, inflammation, and cellular aging synergistically.
Natural & Safe: Non-GMO, GRAS-certified, and no significant drug interactions (LD50 >5,000 mg/kg).
Synergistic Potential: Complements resveratrol, CoQ10, and vitamin C in formulations.
Global Compliance
USA: FDA GRAS (GRN 001315) for dietary supplements and beverages.
EU: EFSA-approved health claims for "blood flow improvement" (ID 3201) and "antioxidant protection" (ID 3202).
China: Listed in Pharmacopoeia (2020 Edition) for cardiovascular support.
Certifications: ISO 22000, USDA Organic, Halal, Kosher, Non-GMO Project Verified.
Technical Note
Storage: 24-month stability in airtight, light-protected containers at ≤25°C (humidity <60%).
Dosage: 200-600 mg/day standardized to 40% punicalagins (clinical effective range for cardiovascular support).
Customization: Available in punicalagin (30%-60%) or ellagic acid (5%-15%) concentrations, with full COA, MSDS, and stability data.
MOQ: 1kg (R&D), 20kg drum (commercial scale).
Company Profile
Audited Supplier 
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