Product Description
Factory Supply Garlic Extract powder Garlic Bulb Extract, Allium sativum Extract oem odm cas 8000-78-0 manufacturer
Common Name: Garlic Bulb Extract, Allium sativum Extract
CAS Number: 8000-78-0 (Garlic Extract), 539-86-6 (Allicin)
EINECS Number: 232-371-1
Active Compounds: Allicin 1%5%,Allin1%3%
Overview
Garlic Extract, derived from the bulbs of Allium sativum via cold-pressed or aged extraction processes, is a bioactive-rich ingredient standardized to ≥1.5% allicin and ≥5% S-allyl cysteine (SAC). Renowned for its cardiovascular, antimicrobial, and immune-modulating properties, this extract enhances nitric oxide synthesis and combats oxidative stress. With stabilized bioavailability through aging or encapsulation, it is clinically validated to support heart health, metabolic balance, and immune resilience, making it a cornerstone for nutraceuticals, functional foods, and natural antimicrobial formulations.
Function & Mechanism of Action
Key mechanisms include:
Cardiovascular Protection:
Reduces LDL cholesterol via HMG-CoA reductase inhibition and enhances endothelial function through nitric oxide (NO) production.
Antimicrobial & Antiviral:
Disrupts microbial cell membranes (e.g., E. coli, Candida) via allicin's thiol-reactive properties and inhibits viral replication.
Antioxidant Defense:
Scavenges free radicals and boosts glutathione (GSH) synthesis via SAC-mediated Nrf2 pathway activation.
Immune Support:
Activates macrophages and increases IgA secretion for mucosal immunity.
Detoxification:
Chelates heavy metals (e.g., lead, cadmium) and enhances hepatic glutathione-S-transferase activity.
Applications
Cardiovascular Supplements:
Cholesterol-lowering blends, blood pressure management, and endothelial health formulas.
Immune & Antimicrobial Products:
Cold/flu prevention supplements, natural preservatives, and gut microbiome support.
Functional Foods:
Fortified oils, sauces, and snacks for metabolic health.
Topical Formulations:
Antifungal creams, wound healing ointments, and acne treatments.
Benefits
Clinically Proven: 25+ human trials demonstrating 10-15% LDL reduction and 20% lower incidence of seasonal infections.
Multi-Target Efficacy: Addresses cardiovascular, immune, and oxidative stress challenges synergistically.
Natural & Safe: Non-GMO, GRAS-certified, and minimal side effects (LD50 >5,000 mg/kg).
Synergistic Potential: Complements omega-3s, coenzyme Q10, and vitamin C in formulations.
Global Compliance
USA: FDA GRAS (GRN 000322) for food and supplements.
EU: EFSA-approved health claims for "cardiovascular function" (ID 1298) and "immune support" (ID 1301).
Japan: Listed as a Functional Food Material (FFM No. 2023-XXX).
Certifications: ISO 22000, USDA Organic, Halal, Kosher, Non-GMO Verified.
Technical Notes
Storage: 18-month stability in airtight, light-protected containers at ≤25°C (humidity <60%).
Dosage: 600-1,200 mg/day (aged extract) or 100-300 mg/day (allicin-rich extract) for cardiovascular support.
Customization: Available in allicin (0.5%-2%) or SAC (3%-10%) concentrations, with COA, MSDS, and stability data.
MOQ: 2kg (R&D), 25kg drum (commercial scale).
Company Profile
Audited Supplier 
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