Product Description
Factory Supply Dandelion Extract powder Taraxacum officinale Extract Standardized Detox Bioactive oem odm cas 327-97-9 manufacturer
Dandelion Extract
Common Name: Taraxacum officinale Extract, Standardized Detox Bioactive
CAS Number: 68990-74-9 / 327-97-9
Active Compounds:4:1/10:1
Overview
Dandelion Extract, sourced from the roots and leaves of Taraxacum officinale via ethanol-water extraction, is a potent detoxifying agent with dual hepatic and renal support. Standardized to bioactive chicoric acid and chlorogenic acid, it demonstrates 8x higher antioxidant capacity than vitamin C (ORAC ≥200,000 μmol TE/g) and enhances bile secretion by 40% in clinical trials. Proven to reduce liver enzyme levels (ALT/AST) and promote diuresis, it is a key ingredient in liver detox formulations, digestive health supplements, and natural diuretic products.
Function & Mechanism of Action
Key mechanisms include:
Hepatoprotection:
Activates Nrf2 pathway to upregulate glutathione synthesis (validated in 12+ preclinical studies).
Diuretic Action:
Inhibits renal sodium reabsorption via potassium-sparing mechanisms (EMA monograph compliant).
Anti-Inflammatory:
Suppresses NF-κB and COX-2 pathways, reducing TNF-α and IL-6 production.
Digestive Stimulation:
Enhances pancreatic lipase activity and gut motility through bitter sesquiterpene lactones.
Antioxidant Defense:
Neutralizes ROS via redox cycling of chicoric acid and chlorogenic acid.
Applications
Nutraceuticals:
Liver detox capsules, kidney support formulas, and bloating relief tablets.
Functional Foods:
Detox teas, digestive bitters, and prebiotic-enriched snacks.
Cosmeceuticals:
Anti-acne serums, cellulite reduction creams, and antioxidant facial toners.
Traditional Medicine:
Synergistic use with milk thistle or artichoke extract in hepatoprotective blends.
Benefits
Clinically Validated: 15+ human studies on liver function and diuretic efficacy (ChP 2020 listed).
Dual Organ Support: Simultaneously targets hepatic detoxification and renal filtration.
Non-Toxic: Safe for long-term use (LD50>5,000 mg/kg in rodents).
Cost-Effective: 500-1,000 mg/day dosage matches 200 mg silymarin liver protection effects.
Global Compliance
China: Approved as a Traditional Chinese Medicine (TCM) for "heat-clearing" (ChP 2020).
USA: FDA GRAS (Self-Affirmed), DSHEA-compliant dietary ingredient.
EU: EFSA Novel Food compliant (EU 2015/2283), Traditional Herbal Registration eligible.
Certifications: ISO 22000, Organic (USDA/NOP), Halal, Non-GMO.
Technical Notes
Storage: 24-month stability at ≤25°C in vacuum-sealed, light-resistant packaging.
Customization: Available in 5%-20% chicoric acid grades with COA/MSDS
MOQ: 1kg (R&D samples), 15kg bulk orders.
Synergy Pairings: Combines with milk thistle or turmeric for amplified detoxification effects.
Company Profile
Audited Supplier 
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