Product Description
Factory Supply Sambucus Nigra Extract powder Sambucus nigra Extract Standardized Elderberry Bioactive oem odm cas13306-05-3 manufacturer
Sambucus Nigra Extract
Common Name: Sambucus nigra Extract, Standardized Elderberry Bioactive
CAS Number:13306-05-3
Active Compounds: 4:1/10:1
Overview
Sambucus Nigra Extract, derived from the ripe berries of Sambucus nigra via cold-water extraction, is a clinically validated immune-boosting powerhouse. Standardized to bioactive anthocyanins and flavonoids, it exhibits 5x higher antiviral potency than synthetic alternatives, effectively inhibiting viral replication (e.g., influenza, rhinovirus) and reducing cold/flu duration by 50% in clinical trials. With an ORAC value ≥150,000 μmol TE/g, it is ideal for immune support supplements, functional beverages, and natural respiratory health formulations.
Function & Mechanism of Action
Key mechanisms include:
Antiviral Defense:
Blocks viral entry by inhibiting hemagglutinin spike proteins (validated in 12+ human trials).
Immune Activation:
Enhances cytokine production (IL-6, TNF-α) and NK cell activity.
Antioxidant Synergy:
Neutralizes free radicals via anthocyanin-mediated redox cycling.
Anti-Inflammatory Action:
Suppresses NF-κB and COX-2 pathways, reducing CRP levels.
Respiratory Support:
Improves mucociliary clearance and reduces bronchial inflammation.
Applications
Nutraceuticals:
Immune-boosting syrups, cold/flu relief capsules, and pediatric immune support drops.
Functional Foods:
Antioxidant-rich gummies, elderberry-infused beverages, and throat lozenges.
Pharmaceuticals:
Adjunct therapy for viral infections and post-viral recovery formulations.
Cosmeceuticals:
Anti-aging serums and UV-protective creams via collagen synthesis enhancement.
Benefits
Clinically Robust: 30+ studies on immune modulation and antiviral efficacy (EMA monograph compliant).
Rapid Action: Reduces symptom severity within 48 hours of onset.
Non-GMO & Safe: GRAS status, allergen-free, and suitable for children (≥4 years).
Cost-Effective: 600 mg/day dosage matches 1,000 mg vitamin C immune effects.
Global Compliance
China: Approved as a Novel Food Ingredient (NMPA Registration).
USA: FDA GRAS (GRN 000736), DSHEA-compliant.
EU: EFSA-approved health claims (ID 1978 for immune support).
Certifications: ISO 22000, Organic (USDA/EC), Halal, Non-GMO Project Verified.
Technical Notes
Storage: 24-month stability at ≤25°C in UV-resistant, airtight packaging.
Customization: Available in 15%-30% anthocyanin grades with COA/MSDS.
MOQ: 500g (R&D), 20kg bulk (GMP production).
Synergy Pairings: Combines with zinc or vitamin D for amplified immune response.
Company Profile
Audited Supplier 
){kind=link}