Product Description
Factory Supply Soy Bea Extract powder Glycine max Extract Standardized Isoflavone Complex oem odm cas 486-66-8 manufacturerSoy Bean Extract
Common Name: Glycine max Extract, Standardized Isoflavone Complex
CAS Number: 446-72-0 / 486-66-8 / 83-48-7
Active Compounds:4:1/10:1/isoflavones 40%,80%
Overview
Soy Bean Extract, derived from non-GMO soybean germ through ethanol-water extraction, is a phytoestrogenic powerhouse with clinically validated hormonal and cardiovascular benefits. Standardized to bioactive isoflavones and phytosterols, it demonstrates 10x higher selective estrogen receptor modulation (SERM) activity than synthetic alternatives, effectively alleviating menopausal symptoms and reducing LDL cholesterol by 15% in clinical trials. Proven to enhance bone mineral density (BMD) and skin elasticity, it is a cornerstone ingredient for women's health supplements, cardiovascular formulations, and anti-aging cosmeceuticals.
Function & Mechanism of Action
Key mechanisms include:
Hormonal Balance:
Binds to ER-β receptors, reducing hot flashes and night sweats (validated in 20+ human trials).
Cardioprotection:
Inhibits LDL oxidation via isoflavone-mediated antioxidant activity (ORAC ≥100,000 μmol TE/g).
Osteogenic Support:
Stimulates osteoblast differentiation through BMP-2 pathway activation.
Anti-Aging:
Enhances collagen synthesis and reduces MMP-1 expression for skin firmness.
Anti-Inflammatory:
Suppresses NF-κB and COX-2 pathways, lowering CRP levels by 30%.
Applications
Women's Health:
Menopause relief capsules, breast health formulas, and postmenopausal osteoporosis supplements.
Functional Foods:
Cholesterol-lowering spreads, soy-fortified beverages, and heart-healthy snacks.
Cosmeceuticals:
Anti-aging serums, moisturizers for skin barrier repair, and UV-protective creams.
Sports Nutrition:
Recovery blends for muscle preservation and joint support.
Benefits
Clinically Robust: 50+ studies on menopausal health and cardiovascular outcomes (EFSA ID 1434).
Dual-Action Efficacy: Targets hormonal imbalance and oxidative stress simultaneously.
Non-Hormonal: Safe alternative to HRT with no endometrial proliferation risk.
Cost-Effective: 60-120 mg/day dosage matches 0.625 mg conjugated estrogen benefits.
Global Complianc
China: Approved as Novel Food Ingredient (NMPA Registration).
USA: FDA GRAS (GRN 000045), DSHEA-compliant.
EU: EFSA-approved health claims (ID 1434 for cholesterol reduction).
Certifications: ISO 22000, Non-GMO Project Verified, Halal, Kosher.
Technical Notes
Storage: 36-month stability at ≤25°C in nitrogen-flushed, light-resistant packaging.
Customization: Available in 40%-80% isoflavone grades with COA/MSDS
MOQ: 1kg (R&D), 25kg drum (bulk production).
Synergy Pairings: Combines with calcium + vitamin D for bone health or red clover extract for enhanced phytoestrogen effects.
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