Product Description
Factory Supply Calcium Butyrate powder: Butyrate Calcium, Calcium Butyric Acid oem odm cas 5743-36-2 manufacturer
Calcium Butyrate
Common Name: Butyrate Calcium, Calcium Butyric Acid
CAS Number: 5743-36-2
Purity: ≥98.0% (by HPLC)
Overview
Calcium Butyrate, a short-chain fatty acid salt composed of butyric acid and calcium ions, is widely used in gut health management, anti-inflammatory, and immune regulation. As a precursor of butyrate, it releases butyric acid in the intestines, directly acting on epithelial cells to promote mucosal repair, inhibit pathogenic bacteria, and modulate immune responses. Compared to sodium butyrate, the calcium salt form offers enhanced stability and dual functionality (butyrate + calcium), making it ideal for food, pharmaceutical, and feed additive applications.
Function & Mechanism of Action
Calcium Butyrate exerts its effects through:
Intestinal Mucosal Repair:
Hydrolyzed to butyrate in the colon, providing energy to epithelial cells for proliferation and barrier restoration.
Antimicrobial & Microbiota Modulation:
Suppresses pathogens (e.g., Salmonella, E. coli) while promoting probiotics (e.g., Bifidobacteria).
Immune Regulation:
Activates G-protein-coupled receptors (GPR109A/43), downregulates pro-inflammatory cytokines (e.g., TNF-α, IL-6).
Calcium Supplementation:
Provides bioavailable calcium for bone health and neural signaling.
Its superior stability (acid-resistant) and dual action make it optimal for chronic gut disease management.
Applications
· Inflammatory Bowel Disease (IBD):
Adjunctive therapy for ulcerative colitis and Crohn's disease.
· Antibiotic-Associated Diarrhea:
Restores microbiota balance post-antibiotic use, preventing C. difficile infection.
· Metabolic Syndrome:
Improves resistance via gut microbiota modulation.
· Animal Feed Additive:
Enhances livestock gut health and feed efficiency, reducing antibiotic reliance.
Benefits
Dual Action: Combines butyrate delivery with calcium supplementation.
Targeted Release: Calcium salt resists gastric degradation for colon-specific delivery.
Regulatory Compliance: Meets China GB 2760-2014 and EU EFSA standards.
Versatility: Suitable for pharmaceuticals, functional foods, and animal feed.
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