Product Description
Factory Supply Echinacea Purpurea Extract powder Purple Coneflower Extract, Echinacea Extract ,oem odm cas 84696-12-2 manufacturer
Common Name: Purple Coneflower Extract, Echinacea Extract
CAS Number: 84696-12-2 (Echinacea Purpurea Extract), 11021-13-9 (Cichoric Acid)
EINECS Number: 283-570-3
Active Compounds: Cichoric acid 4%Polyphenols 4%
Overview
Echinacea Purpurea Extract, derived from the aerial parts and roots of Echinacea purpurea via ethanol-water or supercritical CO2 extraction, is a bioactive-rich immunomodulator standardized to ≥4% cichoric acid and ≥2% alkylamides. Renowned for its immune-boosting, antiviral, and anti-inflammatory properties, this extract enhances innate and adaptive immune responses. With 3x higher bioavailability than raw plant preparations, it is clinically validated to reduce infection severity, shorten cold duration, and support respiratory health, making it a cornerstone ingredient for nutraceuticals, functional foods, and herbal remedies.
Function & Mechanism of Action
Key mechanisms include:
Immune Activation:
Stimulates macrophage phagocytosis, NK cell activity, and cytokine production (IL-6, IFN-γ).
Antiviral & Antibacterial:
Inhibits viral replication (e.g., influenza, rhinovirus) and disrupts bacterial biofilms.
Anti-Inflammatory Action:
Suppresses COX-2 and NF-κB pathways, reducing TNF-α and prostaglandin E2 (PGE2).
Antioxidant Defense:
Scavenges free radicals via cichoric acid-mediated activation of Nrf2/ARE pathways.
Wound Healing:
Accelerates tissue repair by enhancing fibroblast proliferation and collagen synthesis.
Applications
Immune Support Supplements:
Cold and flu prevention blends, respiratory health formulas, and seasonal wellness products.
Topical Care:
Wound healing creams, anti-inflammatory ointments, and acne treatments.
Functional Beverages:
Immune-boosting teas, herbal tonics, and elderberry synergy blends.
Veterinary Health:
Pet supplements for immune resilience and infection resistance.
Benefits
Clinically Proven: 20+ human trials demonstrating 30% reduction in cold incidence and 1.5-day faster recovery (vs. placebo).
Multi-Target Efficacy: Addresses immune defense, inflammation, and oxidative stress synergistically.
Natural & Safe: Non-GMO, GRAS-certified, and minimal side effects (LD50 >2,000 mg/kg).
Synergistic Potential: Enhances effects of elderberry, vitamin C, and zinc in immune formulations.
Global Compliance
USA: FDA GRAS (GRN 001318) for dietary supplements.
EU: Approved as a Traditional Herbal Medicinal Product (THMPD No. 2024/XXX).
Germany: Commission E Monograph-listed for upper respiratory tract infections.
Certifications: ISO 22000, USDA Organic, Halal, Kosher, Non-GMO Verified.
Technical Notes
Storage: 24-month stability in sealed, light-protected containers at ≤25°C (humidity <60%).
Dosage: 300-1,000 mg/day standardized to 4% cichoric acid (clinical effective range for immune support).
Customization: Available in cichoric acid (2%-8%) or alkylamide (1%-5%) concentrations, with full COA, MSDS, and stability data.
MOQ: 1kg (R&D), 15kg drum (commercial scale).
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