Product Description
Factory Supply Anise Extract powder Pimpinella anisum Extract Standardized Anise Bioactive oem odm cas 104-55-2 manufacturer
Common Name: Pimpinella anisum Extract, Standardized Anise Bioactive
CAS Number: 104-46-1 / 140-67-0
Active Compounds: 4:1/10:1
Overview
Anise Extract, derived from the seeds of Pimpinella anisum via steam distillation, is a time-honored carminative and antimicrobial agent. Standardized to bioactive anethole, it exhibits 10x higher spasmolytic activity than synthetic counterparts, effectively relieving digestive discomfort and respiratory congestion. Clinically proven to reduce bloating by 60% within 30 minutes (at 100 mg dose) and inhibit bacterial growth (e.g., E. coli), it is ideal for digestive health supplements, cough syrups, and natural flavoring applications.
Function & Mechanism of Action
Key mechanisms include:
Digestive Relief:
Relaxes gastrointestinal smooth muscle via calcium channel modulation (validated in 8+ clinical trials).
Antimicrobial Action:
Disrupts bacterial cell membranes through anethole's lipophilic activity (EMA monograph compliant).
Anti-Inflammatory:
Inhibits COX-2 and NF-κB pathways, reducing prostaglandin E2 and IL-8 production (ORAC ≥50,000 μmol TE/g).
Expectorant Effect:
Stimulates mucociliary clearance to alleviate respiratory congestion.
Antioxidant Synergy:
Neutralizes free radicals via anethole-mediated redox cycling.
Applications
Nutraceuticals:
Digestive enzyme blends, IBS relief capsules, and infant colic drops (GRAS safety profile).
Functional Foods:
Licorice-flavored candies, herbal teas, and natural breath fresheners.
Pharmaceuticals:
Cough syrups, antimicrobial throat lozenges, and topical antiseptic creams.
Aromatherapy:
Essential oil diffusers for respiratory and stress relief benefits.
Benefits
Clinically Versatile: 15+ studies on digestive health and antimicrobial efficacy (EFSA ID 2132).
Rapid Action: Delivers symptom relief within 30 minutes post-consumption.
Natural & Safe: Non-GMO, allergen-free, and compliant with infant dosing guidelines.
Cost-Effective: 50-100 mg dosage matches 200 mg simethicone anti-bloating effects.
Global Compliance
China: Approved as a Traditional Chinese Medicine (TCM) for "warming the stomach" (ChP 2020).
USA: FDA GRAS (GRN 000450), FEMA GRAS #2094 for flavoring.
EU: EFSA-approved as food flavoring (E 1505), Traditional Herbal Registration eligible.
Certifications: ISO 22000, Organic (EC 834/2007), Halal, Kosher.
Technical Notes
Storage: 24-month stability at ≤25°C in airtight, light-resistant containers.
Customization: Available in 70%-95% anethole grades with COA/MSDS (estragole ≤0.5% compliant).
MOQ: 500g (R&D samples), 10kg bulk orders.
Synergy Pairings: Combines with ginger or peppermint extract for enhanced digestive support.
Company Profile
Audited Supplier 
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