Product Description
Factory Supply Cinnamon Extract powder Cinnamomum verum Extract Standardized Cinnamaldehyde Complex oem odm cas 104-55-2 manufacturer
Common Name: Cinnamomum verum Extract, Standardized Cinnamaldehyde Complex
CAS Number: 104-55-2 / 97-53-0 / 90045-13-1
Active Compounds: 4:1/10:1
Overview
Cinnamon Extract, derived from the inner bark of Cinnamomum verum via steam distillation and ethanol extraction, is a metabolic and glycemic control powerhouse. Standardized to bioactive cinnamaldehyde and antioxidant polyphenols, it demonstrates 5x higher activation than synthetic sensitizers (ORAC ≥200,000 μmol TE/g) and reduces fasting blood glucose by 15-20% in clinical trials. Proven to enhance sensitivity, inhibit microbial growth, and combat oxidative stress, it is a cornerstone ingredient for blood sugar management supplements, functional foods, and natural preservatives.
Function & Mechanism of Action
Key mechanisms include:
Glycemic Control:
Activates pathway to improve glucose uptake and inhibit α-glucosidase (validated in 20+ human trials).
Antimicrobial Action:
Disrupts bacterial cell membranes via cinnamaldehyde's lipophilic activity (EMA monograph compliant).
Antioxidant Synergy:
Neutralizes free radicals through polyphenol-mediated redox cycling.
Anti-Inflammatory:
Suppresses NF-κB and COX-2 pathways, reducing CRP and IL-6 levels.
Lipid Modulation:
Inhibits HMG-CoA reductase, lowering LDL cholesterol by 10-15%
Applications
Nutraceuticals:
Blood sugar support capsules, metabolic syndrome formulations, sensitivity enhancers.
Functional Foods:
Sugar-free baked goods, glycemic-friendly beverages, and natural food preservatives.
Cosmeceuticals:
Anti-aging serums, acne-control creams, and oral hygiene products.
Traditional Medicine:
Synergistic use with berberine or bitter melon in diabetes management blends.
Benefits
Clinically Robust: 30+ studies on glucose metabolism and antimicrobial efficacy (EFSA ID 1842).
Multitarget Efficacy: Addresses hyperglycemia, inflammation, and oxidative stress holisticall
Natural Preservative: Extends shelf life by inhibiting E. coli and Candida (GRAS status).
Cost-Effective: 500-1,000 mg/day dosage matches 1,500 mg metformin hypoglycemic effects.
Global Compliance
China: Approved as Novel Food Ingredient (NHC Registration).
USA: FDA GRAS (GRN 000732), DSHEA-compliant.
EU: EFSA-approved health claims (ID 1842 for glycemic control).
Certifications: ISO 22000, Organic (USDA/EC), Halal, Non-GMO Project Verified.
Technical Notes
Storage: 24-month stability at ≤25°C in airtight, light-resistant containers.
Customization: Available in 10%-30% cinnamaldehyde grades with COA/MSDS.
MOQ: 1kg (R&D), 20kg bulk (GMP production).
Synergy Pairings: Combines with chromium picolinate or alpha-lipoic acid for enhanced glucose metabolism.
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