Product Description
Factory Supply Ashwaganda Extract powder Withania somnifera Extract, Indian Ginseng Extract oem odm cas 8057-62-3 manufacturer
Common Name: Withania somnifera Extract, Indian Ginseng Extract
CAS Number: 8057-62-3
Active Compounds:4:1/10:1/Withanolide glycosides1.5%7%
Overview
Ashwagandha Extract, derived from the roots of Withania somnifera through ethanol-water extraction, is a bioactive-rich adaptogen standardized to ≥5% withanolides and ≥1% withaferin A. Renowned for its stress-modulating, neuroprotective, and energy-enhancing properties, this extract targets cortisol regulation, oxidative stress, and mitochondrial function. With 4x higher bioavailability than raw root preparations, it is clinically validated to support stress resilience, cognitive performance, and physical endurance, making it a cornerstone ingredient for nutraceuticals, functional foods, and holistic wellness formulations.
Function & Mechanism of Action
Key mechanisms include:
Stress & Anxiety Reduction:
Lowers cortisol levels via HPA axis modulation and enhances GABA receptor activity.
Cognitive Enhancement:
Promotes dendrite formation and acetylcholine synthesis, improving memory and focus.
Immune Support:
Activates NK cells and increases IgG antibodies for robust immune defense.
Anti-Inflammatory & Antioxidant:
Inhibits NF-κB and COX-2 pathways while boosting glutathione peroxidase activity.
Muscle Strength & Recovery:
Increases mitochondrial ATP production and reduces exercise-induced muscle damage (via creatine kinase reduction).
Applications
Stress & Mood Formulations:
Adaptogenic blends, anxiety relief supplements, and adrenal support products.
Sports Nutrition:
Pre-workout energy boosters, post-exercise recovery formulas, and muscle growth aids.
Cognitive Health:
Nootropic stacks for memory enhancement and age-related cognitive decline.
Immune Boosters:
Synergistic blends with elderberry, echinacea, or zinc for year-round wellness.
Women's Health:
Menopause support for hormonal balance and fatigue management.
Benefits
Clinically Proven: 20+ human trials demonstrating 20-30% cortisol reduction, 15% improved sleep quality, and 10% muscle strength gains.
Multi-Target Adaptogen: Addresses stress, inflammation, immunity, and energy metabolism holistically.
Natural & Safe: Non-habit forming, GRAS-certified, and no significant drug interactions (LD50 >2,000 mg/kg).
Synergistic Potential: Enhances effects of rhodiola, L-theanine, and magnesium in formulations.
Global Compliance
India: Approved as Ayurvedic Medicine (Ayush Standard AS-XXXX).
USA: FDA GRAS (GRN 000934) for dietary supplements and beverages.
EU: EFSA Novel Food approval pending (2024/Q3).
Certifications: ISO 22000, USDA Organic, Halal, Kosher, Non-GMO Verified.
Technical Notes
Storage: 24-month stability in sealed, light-protected containers at ≤25°C (humidity <60%).
Dosage: 300-600 mg/day standardized to 5% withanolides (clinical effective range for stress support).
Customization: Available in withanolide concentrations (2%-10%) or withaferin A (0.5%-3%), with full COA, MSDS, and stability data.
MOQ: 2kg (R&D), 25kg drum (commercial scale).
Company Profile
Audited Supplier 
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