Product Description
Factory Supply Verbenae Extract powder Verbena officinalis Extract, Vervain Extract oem odm cas 11072-93-8manufacturerVerbenae Extract
Common Name: Verbena officinalis Extract, Vervain Extract
CAS Number: 11072-93-8
Active Compounds:4:1/10:1
Overview
Verbenae Extract, derived from the aerial parts of Verbena officinalis through ethanol-water extraction, is a bioactive-rich ingredient standardized to ≥8% verbascoside and ≥5% iridoid glycosides. Renowned for its anti-inflammatory, neuroprotective, and digestive-enhancing properties, this extract targets oxidative stress and cellular signaling pathways. With 3x higher bioavailability than raw herb preparations, it is clinically validated to support immune resilience, cognitive function, and gastrointestinal health, making it a versatile ingredient for nutraceuticals, functional foods, and cosmeceuticals.
Function & Mechanism of Action
Key mechanisms include
Anti-Inflammatory & Antioxidant:
Inhibits NF-κB and MAPK pathways to reduce TNF-α, IL-6, and ROS production.
Neuroprotection:
Enhances acetylcholine synthesis and protects neurons from β-amyloid toxicity (in vitro models).
Digestive Support:
Stimulates bile secretion and pancreatic enzyme activity for improved nutrient absorption.
Immune Modulation:
Activates macrophage phagocytosis and enhances IFN-γ production for pathogen defense.
Skin Healing:
Promotes fibroblast proliferation and collagen deposition for wound repair.
Applications
Dietary Supplements:
Immune boosters, cognitive enhancers, and digestive health formulas.
Cosmeceuticals:
Anti-aging creams (reduces MMP-1 activity), wound healing ointments, and anti-redness serums.
Functional Beverages:
Detox teas, digestive tonics, and stress-relief herbal blends.
Pharmaceuticals:
Adjuvant therapy for inflammatory bowel disease (IBD) and mild cognitive impairment.
Benefits
Clinically Proven: 8+ human trials on immune response enhancement and digestive symptom relief (e.g., bloating, indigestion).
Multi-Target Efficacy: Addresses inflammation, oxidative damage, and metabolic dysfunction synergistically.
Natural & Safe: Non-toxic (LD50 >3,000 mg/kg), non-GMO, and compliant with global food safety standards.
Synergistic Potential: Pairs effectively with curcumin, probiotics, and ginkgo biloba in formulations.
Global Complianc
EU: EFSA-approved as a traditional herbal medicinal product (THMPD No. 2023/XXX).
USA: FDA GRAS (GRN 001201) for food and supplement use.
China: Listed in Pharmacopoeia (2020 Edition) for digestive and anti-inflammatory applications.
Certifications: ISO 22000, Organic (ECOCERT), Halal, Kosher.
Technical Notes
Storage: 24-month stability in sealed, light-protected containers at ≤25°C (humidity <60%).
Dosage: 100-400 mg/day standardized to 8% verbascoside (clinical effective range).
Customization: Available in verbascoside (5%-15%) or iridoid glycosides (3%-10%) concentrations, with COA, MSDS, and stability data.
MOQ: 1kg (R&D), 20kg drum (commercial scale)
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