Product Description
Factory Supply Phytosterol powder Plant Sterols, Phytosterol Esters oem odm cas 83-46-5 manufacturer
Common Name: Plant Sterols, Phytosterol Esters
CAS Number: 83-46-5
Active Compounds:90% /99%
Overview
Phytosterol Complex, derived from non-GMO plant sources (soybean, pine, or sunflower) through molecular distillation, is a cholesterol-lowering powerhouse with a structure analogous to human cholesterol. Clinically proven to reduce LDL cholesterol by 10-15% at 2g/day dosage (FDA-authorized health claim), it competitively inhibits cholesterol absorption in the gut while modulating lipid metabolism via LXR-α/PPAR-γ pathways. Ideal for functional foods, heart health supplements, and lipid-modifying nutraceuticals.
Function & Mechanism of Action
Key mechanisms include:
Cholesterol Displacement:
Competes with dietary cholesterol for micelle incorporation, reducing intestinal absorption by 30-50%.
Lipid Metabolism:
Activates ABCG5/G8 transporters to enhance biliary cholesterol excretion.
Anti-Inflammatory:
Inhibits NF-κB signaling and CRP levels in metabolic syndrome (validated in 15+ clinical trials).
Antioxidant Synergy:
Scavenges lipid peroxides via conjugated diene reduction (ORAC equivalent ≥20,000 μmol TE/g).
Hormonal Balance:
Modulates estrogen receptor β (ERβ) activity for menopausal symptom relief.
Applications
Functional Foods:
Cholesterol-lowering margarines, dairy products, and snack bars (EFSA Article 13.5 claim).
Nutraceuticals:
Cardiovascular support softgels, metabolic syndrome formulations.
Cosmeceuticals:
Barrier-repair creams, anti-aging serums via ceramide synthesis enhancement.
Pharmaceuticals:
Adjuvant therapy for familial hypercholesterolemia (FDA Monograph OTC)
Benefits
Clinically Authorized: FDA/EFSA-approved cholesterol reduction claim.
Broad-Spectrum Action: Targets LDL oxidation, inflammation, and lipid absorption.
Thermostable: Maintains efficacy in baked/processed foods (up to 180°C).
Cost-Effective: 1.5-3g/day dosage achieves 10% LDL reduction (vs. 10mg statins).
Global Compliance
China: GB 2760-2014 as functional food additive (INS 499).
USA: FDA GRAS (GRN 000085), authorized health claim (21 CFR 101.83).
EU: EFSA-approved (ID 1494), Novel Food compliant.
Certifications: ISO 22000, Non-GMO Project Verified, Kosher/Halal.
Technical Notes
Storage: 36-month stability at ≤25°C in nitrogen-flushed packaging.
Customization: Free/esterified forms (60-95% purity), COA with sterol profile.
MOQ: 10kg (food-grade), 1kg (R&D samples).
Synergy Pairings: Combines with omega-3 or soluble fiber for enhanced lipid management.
Company Profile
Audited Supplier 
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